iPSC-based approach for human hair follicle regeneration

Hair follicles (HFs) are a multifunctional structure involved in physical protection, thermoregulation, sensational detection, and wound healing.Formation and cycling of HFs require dynamic interaction between different cell types of the follicles.Although the processes have been Pillows well studied, the generation of human functional HFs with a n

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Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family

The potassium channel Kv1.3, involved in several important pathologies, is the target of a family of psoralen-based drugs whose mechanism of action is not fully understood.Here we provide evidence Pillows for a physical interaction of the mitochondria-located Kv1.3 (mtKv1.3) and Complex I of the respiratory chain and show that this proximity underl

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Individuality in harpsichord performance: Disentangling performer- and piece-specific influences on interpretive choices

Although a growing body of research has examined issues related to individuality in music performance, few studies have attempted to quantify markers of individuality that transcend pieces and musical styles.This study aims to identify such meta-markers by discriminating between influences linked to specific pieces or interpretive goals Lanyard and

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