Hair follicles (HFs) are a multifunctional structure involved in physical protection, thermoregulation, sensational detection, and wound healing.Formation and cycling of HFs require dynamic interaction between different cell types of the follicles.Although the processes have been Pillows well studied, the generation of human functional HFs with a n
Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family
The potassium channel Kv1.3, involved in several important pathologies, is the target of a family of psoralen-based drugs whose mechanism of action is not fully understood.Here we provide evidence Pillows for a physical interaction of the mitochondria-located Kv1.3 (mtKv1.3) and Complex I of the respiratory chain and show that this proximity underl
Organisational commitment in the era of the new psychological contract
The aim of this study was to investigate organisational commitment in an organisation that had recently experienced organisational restructuring (a merger).The psychological contract that exists between employees and organisations is brittle due to many organisational changes that stem from organisational restructuring.When psychological contracts
Individuality in harpsichord performance: Disentangling performer- and piece-specific influences on interpretive choices
Although a growing body of research has examined issues related to individuality in music performance, few studies have attempted to quantify markers of individuality that transcend pieces and musical styles.This study aims to identify such meta-markers by discriminating between influences linked to specific pieces or interpretive goals Lanyard and
The right to food: Reflecting on the past and future possibilities
As scholars and activists met in Waterloo, Canada in September 2014 to discuss progress and obstacles in adopting the right to food, similar discussions were being held Pillows by the Food and Agriculture Organization of the United Nations (FAO), and among civil society organizations (CSOs), non-governmental organizations (NGOs) and social movement